基于基因组信息估计中国美利奴羊羊毛纤维直径和弯曲性状的遗传参数

doi:10.16431/j.cnki.1671-7236.2025.10.026

中国畜牧兽医 ›› 2025, Vol. 52 ›› Issue (10): 4809-4821.doi: 10.16431/j.cnki.1671-7236.2025.10.026

• 遗传繁育 • 上一篇

基于基因组信息估计中国美利奴羊羊毛纤维直径和弯曲性状的遗传参数

唐丽苹^1,2, 于丽娟², 张彦威², 郑培宇^1,2, 王嘉俊^1,3, 谢梦婉², 马海叶³, 刘璇³, 宋楠楠^1,2, 李婧平³, 岳成广^1,3, 张倩雯^1,3, 李忠慧³, 李文蓉³, 狄江²

1. 新疆农业大学动物科学学院, 乌鲁木齐 830052;
2. 新疆畜牧科学院畜牧研究所, 新疆绒毛用羊遗传育种与繁殖实验室, 农业农村部畜禽资源(羊)评价利用重点实验室, 乌鲁木齐 830011;
3. 新疆畜牧科学院生物技术研究所, 农业农村部草食家畜遗传育种与繁殖重点实验室, 新疆动物生物技术重点实验室, 乌鲁木齐 830026

收稿日期:2025-02-07 发布日期:2025-09-30
通讯作者: 李文蓉, 狄江 E-mail:xjlwr@126.com;dijiang69@163.com
作者简介:唐丽苹，E-mail：1604059062@qq.com。
基金资助:
国家重点研发计划课题：绵羊高繁殖力及优异毛用种质资源精准鉴定(2021YFD1200901)；新疆维吾尔自治区重点实验室开放课题：IRF2BP2基因与被毛类型及纤维直径的相关性研究(2023D04080)

Estimation of Genetic Parameters for Fiber Diameter and Bending Traits of Wool Fibers in Chinese Merino Wool Based on Genomic Information

TANG Liping^1,2, YU Lijuan², ZHANG Yanwei², ZHENG Peiyu^1,2, WANG Jiajun^1,3, XIE Mengwan², MA Haiye³, LIU Xuan³, SONG Nannan^1,2, LI Jingping³, YUE Chengguang^1,3, ZHANG Qianwen^1,3, LI Zhonghui³, LI Wenrong³, DI Jiang²

1. College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China;
2. Key Laboratory of Evaluation and Utilization of Livestock and Poultry Resources (Sheep), Ministry of Agriculture and Rural Affairs, Xinjiang Laboratory of Sheep Genetics, Breeding and Reproduction for Fluff Wool, Institute of Animal Science, Xinjiang Academy of Animal Sciences, Urumqi 830011, China;
3. Xinjiang Key Laboratory of Animal Biotechnology, Key Laboratory of Genetics, Breeding and Reproduction of Grass-fed Livestock, Ministry of Agriculture and Rural Affairs, Institute of Biotechnology, Xinjiang Academy of Animal Sciences, Urumqi 830026, China

Received:2025-02-07 Published:2025-09-30

摘要/Abstract

摘要： 【目的】利用基因组信息估计新疆巩乃斯种羊场中国美利奴羊周岁及成年羊羊毛纤维直径和弯曲性状遗传参数。【方法】对2022—2023年巩乃斯种羊场1 520只周岁羊、836只成年母羊进行全基因组重测序，收集系谱数据，利用OFDA等仪器测定羊毛平均纤维直径(MFD)、纤维直径标准差(FDSD)、纤维直径变异系数(FDCV)、直径<30 μm纤维含量百分比(CF)、沿毛丛方向平均纤维直径标准差(APSD)、弯曲数(CN)、纤维平均曲率(MFC)和纤维弯曲度标准差(FCSD)8个性状，共计18 496条数据信息。分别基于系谱和基因组信息构建亲缘关系矩阵，建立多性状动物模型、利用ASREML软件采用平均信息最大似然法估计性状遗传力、遗传相关和表型相关。【结果】基于系谱信息估计的周岁和成年羊羊毛性状遗传力范围分别为0.066～0.859和0.088～0.782。基于基因组信息估计的周岁羊羊毛性状均为高遗传力性状(0.349～0.684)，成年羊羊毛性状为中到高遗传力性状(0.125～0.941)。其中，中国美利奴羊品种中测定的性状CF、APSD、MFC和FCSD的遗传力在周岁羊分别为0.445、0.403、0.684和0.635，属于高遗传力，在成年羊分别为0.776、0.125、0.471和0.624，属于中到高遗传力。周岁和成年羊基于基因组信息估计的MFD与FDSD呈较高正遗传相关(P＜0.01)，与CF呈较高的负遗传相关(P＜0.01)；MFC与FCSD呈较高正遗传相关(P＜0.01)。【结论】基于基因组信息估计出中国美利奴羊羊毛纤维直径和弯曲性状，周岁羊均为高遗传力，成年羊为中到高遗传力。周岁羊和成年羊CF与MFD间呈较高负遗传相关，MFC与FCSD间遗传相关性和表型相关性均最高。基于基因组信息估计遗传参数提高了准确性，为了解中国美利奴羊群体中纤维直径和弯曲性状变异，为进一步完善育种方案提供了借鉴。

关键词: 中国美利奴羊; 羊毛性状; 系谱; 基因组; 遗传参数

Abstract: 【Objective】 The genetic parameters of wool fiber diameter and bending traits were estimated using genomic information in Chinese Merino sheep from the Xinjiang Gongnaisi sheep farm.【Method】 Whole genome resequencing was performed for 1 520 yearling sheep and 836 adult ewes from 2022 to 2023.Pedigree data were collected,and 8 traits,including mean fiber diameter (MFD),fiber diameter standard deviation (FDSD),fiber diameter coefficient of variation (FDCV),percentage of fiber content with diameter less than 30 μm (CF),standard deviation of average fiber diameter along profile (APSD),curvature number (CN),mean fiber curvature (MFC),and fiber curvature standard deviation (FCSD),were measured using OFDA and other instruments to yield a total of 18 496 data points.Kinship matrices were constructed based on pedigree and genome information respectively,and multi-trait animal models were established to estimate genetic parameters using ASREML software with the average information maximum likelihood method.【Result】 The heritability ranges for wool traits based on pedigree information were 0.066-0.859 and 0.088-0.782 in yearlings and adults respectively,and the heritabilities of all traits based on genomic information were high for yearlings (0.349-0.684),and medium to high for adult ewes (0.125-0.941).The four traits of CF,APSD,CD,and CDSD,investigated for the first time in Chinese Merino sheep,had the higher heritability values of 0.445,0.403,0.684 and 0.635 respectively in yearlings,and moderate to high heritability of 0.776,0.125,0.471,and 0.624 respectively in adult ewes.The MFD estimated based on genomic information in yearlings and adult ewes showed a high positive genetic correlation with FDSD (P＜0.01),and a high negative genetic correlation with CF (P＜0.01);MFC and FCSD showed a high positive genetic correlation (P＜0.01).【Conclusion】 Based on genomic information,it was estimated that the wool fiber diameter and bending traits of Chinese Merino sheep were highly heritable in yearlings ewes,and moderately to highly heritable in adult ewes.There was a high negative genetic correlation between CF and MFD in yearlings and adult ewes,while the genetic and phenotypic correlations between MFC and FCSD were the highest.The estimation of genetic parameters based on genomic information had improved accuracy,providing a reference for understanding the variation in fiber diameter and bending traits in the Chinese Merino sheep population and further improving breeding programs.

Key words: Chinese Merino sheep; wool traits; pedigree; genome; genetic parameters

中图分类号:

S826

唐丽苹, 于丽娟, 张彦威, 郑培宇, 王嘉俊, 谢梦婉, 马海叶, 刘璇, 宋楠楠, 李婧平, 岳成广, 张倩雯, 李忠慧, 李文蓉, 狄江. 基于基因组信息估计中国美利奴羊羊毛纤维直径和弯曲性状的遗传参数[J]. 中国畜牧兽医, 2025, 52(10): 4809-4821.

TANG Liping, YU Lijuan, ZHANG Yanwei, ZHENG Peiyu, WANG Jiajun, XIE Mengwan, MA Haiye, LIU Xuan, SONG Nannan, LI Jingping, YUE Chengguang, ZHANG Qianwen, LI Zhonghui, LI Wenrong, DI Jiang. Estimation of Genetic Parameters for Fiber Diameter and Bending Traits of Wool Fibers in Chinese Merino Wool Based on Genomic Information[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(10): 4809-4821.

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基于基因组信息估计中国美利奴羊羊毛纤维直径和弯曲性状的遗传参数

Estimation of Genetic Parameters for Fiber Diameter and Bending Traits of Wool Fibers in Chinese Merino Wool Based on Genomic Information

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