不同组学测序技术在动物遗传育种中的研究与应用

doi:10.16431/j.cnki.1671-7236.2025.11.025

Abstract

Abstract: Research based on various omics sequencing technologies plays a critical role in advancing animal genetics and breeding.By systematically analyzing sequencing data,it is possible to gain deeper insights into species biology,regulatory mechanisms,and genetic architecture,thereby providing a scientific basis for breeding and production practices.This review summarizes the development of sequencing technologies across genomics,transcriptomics,proteomics,metabolomics,epigenomics,and single-cell transcriptomics,while critically evaluating the strengths and limitations of current omics methodologies.Different omics research techniques and associated software tools are outlined,offering valuable references for researchers in the field.The application of both single-omics and integrative multi-omics approaches in animal genetics and breeding is discussed,the research ideas and processes are analyzed,and the feasible multi-omics integration strategies have been proposed to provide theoretical references for multi-omics research.Furthermore,the current challenges associated with multi-omics research are examined,and potential future directions are proposed.Overall,multi-omics integration facilitates a comprehensive understanding of biological systems by incorporating genomic,transcriptomic,and epigenomic data.This approach provides a robust foundation for precision breeding and targeted genetic improvement,accelerating progress in animal genetics and breeding while establishing multi-omics research as a key direction for future exploration.

Key words: multi-omics; sequencing; breeding; population genetics

CLC Number:

S831

ZHONG Ziqi, XIE Xinfeng, WANG Ziyi, PAN Deyou, SU Zhiqing, FAN Jinwei, XIAO Qian. Research and Application of Various Omics Sequencing Technologies in Animal Genetic Breeding[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(11): 5287-5298.

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Research and Application of Various Omics Sequencing Technologies in Animal Genetic Breeding

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