玉米赤霉烯酮在动物体内的代谢与分子毒性研究进展

doi:10.16431/j.cnki.1671-7236.2023.12.040

Abstract

Abstract: Zearalenone (ZEA) is a mycotoxin produced by the fungi of Fusarium genera,which widely contaminates corn,wheat,barley,and other grains.After metabolism and conversion,ZEA can be distributed throughout the body via the bloodstream,causing damage in liver,kidney,uterus,testis and other organs through estrogenic effects,oxidative damage, cell apoptosis, etc.In recent years,the contamination of ZEA in crops not only poses serious challenges to livestock farming and feed industries but also threatens human health.A deep comprehension of the metabolism and toxic mechanism in animals is particularly essential for developing new prevention strategies to mitigate the negative impacts of ZEA.The author focuses on the absorption,distribution,metabolism and molecular toxicology of ZEA to clarify its toxic mechanism in animals.

Key words: zearalenone; metabolism; molecular toxicology

CLC Number:

S852.4⁺4

DENG Zifeng, WANG Lijuan, WU Xiqiang, YANG Honghui, LI Tingyuan, WANG Lingling. Research Progress on Metabolism and Toxicity of Zearalenone in Animals[J]. China Animal Husbandry & Veterinary Medicine, 2023, 50(12): 5194-5203.

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Research Progress on Metabolism and Toxicity of Zearalenone in Animals

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