肠道菌群对畜禽免疫系统的影响研究进展

doi:10.16431/j.cnki.1671-7236.2025.07.038

Abstract

Abstract: The immune system consists of immune organs,immune cells and immunologically active substances,which can recognize and eliminate pathogens and abnormal cells.The intestinal flora is involved in the body’s digestion,absorption and metabolism,and the regulation of the immune system and nervous system.Intestinal flora is a complex community composed of all microorganisms in the intestinal tract.During the long-term co-evolutionary process,there is a dynamic interplay between the intestinal flora and the host immune system,which affects the host’s intestinal health and immune function,and dysregulation of the intestinal flora can cause inflammatory reactions and diseases in the host.At the same time,intestinal flora can metabolize protein,dietary fiber,primary bile acids,linoleic acids and carbohydrates,and produce a large number of metabolites,such as short-chain fatty acids,bile acids and indole，which affect the interaction between intestinal epithelial cells and immune cells,including host metabolism,intestinal barrier and immune function.At present,there are still some shortcomings in the study of intestinal flora in livestock and poultry,such as incomplete understanding of intestinal flora diversity,unclear function and cooperation mechanism,limitations in research methods and lack of regulatory means.In this paper,the effects of intestinal flora and its metabolites on the immune system of livestock and poultry were systematically reviewed in order to better understand the complex interaction between intestinal flora and immune system of livestock and poultry,and provide theoretical basis for developing new strategies and methods for the prevention and treatment of related diseases.

Key words: intestinal flora; immune system; metabolism; inflammatory response

CLC Number:

S852.4

WANG Haojie, HUA Tian, CHEN Shihao, BI Yulin, JIANG Yong, WANG Zhixiu, CHEN Guohong, BAI Hao, CHANG Guobin. Research Progress on Effects of Intestinal Flora on Immune System of Livestock and Poultry[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(7): 3398-3408.

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Research Progress on Effects of Intestinal Flora on Immune System of Livestock and Poultry

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