女贞子提取物对蛋鸡产蛋高峰后期生产性能和免疫功能的影响

Abstract

Abstract: This trial was conducted to evaluate the effects of Ligustrum lucidum fruits extracts on productive performance and immune function of layer after laying peak period. A total of 180 47-week Hyline brown layers were randomly divided into 4 groups with 3 replicates per group and 15 birds per replicate in a single-factor completely randomized experimental design. The control group were fed a basal diet, the experimental groups Ⅰ, Ⅱ and Ⅲ were fed the basal diet supplemented with 0.05%, 0.10% and 0.15% Ligustrum lucidum fruits extracts, respectively. The results showed as follows， compared with the control group, the daily egg production and laying rate of layer in the three experimental groups were extremely significantly increased (P＜0.01) respectively, the feed/egg in experimental group Ⅲ was extremely significantly decreased by 10.9% (P＜0.01), but among 4 groups the average egg weight and rate of broken or soft egg did not significantly change (P＞0.05); and the content of testosterone in experimental groups Ⅱ and Ⅲ were extremely significantly decreased (P＜0.01), the contents of progesterone, estradiol, immunoglobulins (IgM, IgA) and interleukin-2 (IL-2) in three experimental groups were all extremely significantly increased respectively compared with the control group (P＜0.01). In conclusion, supplement with the Ligustrum lucidum fruits extracts in the basal diet could significantly increase the productive performance and immune function of layer after laying peak period.

Key words:

Ligustrum lucidum fruits extracts; layer; productive performance; immune function

YU Du-juan, MAO Wei, WANG Zhan-bin, LI Yuan-xiao. Effects of Ligustrum lucidum Fruits Extracts on Productive Performance and Immune Function of Layer after Laying Peak Period[J]. China Animal Husbandry & Veterinary Medicine.

References

1 于新友，赵蕾，王艳，等.鸡白细胞介素-2分子生物学和疾病防治应用研究进展［J］.中国畜牧兽医，2011，38(8)：81～84.
2 卢建军. 影响蛋禽产蛋率的主要生理因素［J］.中国家禽，2006，28(1)：42～44.
3 申瑞玲，王俊东.中草药添加剂对蛋鸡抗氧化作用及生产性能的影响［J］.中国兽医科技，2000，30(5): 27～29.
4 石莉莎，单安山.女贞子调节动物免疫功能的研究进展［J］.饲料工业，2009，30(6)：31～35.
5 刘佳，单安山，徐良梅，等. 饲料中添加女贞子原粉对AA肉鸡生产性能和免疫功能的影响［J］.东北农业大学报，2009，40(12)：71～75.
6 向敏, 顾振纶, 梁中琴, 等. 女贞子提取物的体内抗肿瘤作用［J］.江苏药学与临床研究, 2002, 10(1): 13～15.
7 孙燕, 袁瑞荣, 吴迺居, 等. 齐墩果酸的促免疫作用［J］.中国临床药理学杂志, 1988, 4(1): 26～31.
8 张书松，刘忠虎，康相涛，等.白细胞介素2对固始鸡十二指肠黏膜免疫增强作用［J］.中国兽医学报，2009，29(7)：909～913.
9 张玮, 单安山. 女贞子对蛋鸡生产性能和免疫力的影响［J］. 家禽疾病防治，2010,7：997～1001.
10 张瑞霜，徐良梅，单安山.女贞子粉对产蛋后期蛋鸡生产性能、免疫功能和血清生化指标的影响［J］.东北农业大学学报，2011，42(3)：8～12.
11 李杰, 田博, 徐良梅, 等. 不同类型女贞子对 AA 肉鸡生产性能及免疫功能的影响［J］.中国畜牧杂志, 2011, 47(23): 58～62.
12 杨曦，蒋桂华.女贞子的研究开发现状与展望［J］.时珍国医国药，2008，19(12)：2987～2990.
13 陈晓丹.复方女贞子对增强雏鸡免疫功能的影响［J］.中兽医学杂志，2009，3：28～32.
14 金芝贵，金剑，肖忠革，等.女贞子的药理作用及其临床应用进展［J］.药学服务与研究，2011，11(3)：189～192.
15 柏华，牛竹叶，高玉鹏，等.日粮中添加复方中草药添加剂对产蛋后期蛋用种母鸡繁殖性能和新城疫抗体效价的影响［J］.饲料工业，2007，28(9): 50～52.
16 赵澎.从雌、雄激素类似物的中药看中医的双向调节作用［J］.北京中医学院学报，1988，14(6): 41～42.
17 Averill M, Rima K, Patrick B. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis［J］. Annual Review of Immunology, 2006, 24(4): 657～679.
18 Gao D, Li Q, Li Y, et al. Antidiabetic potential of oleanolic acid from Ligustrum lucidum Ait［J］. Canadian Journal of Physiology and Pharmacology, 2007, 85(11): 1076～1083.
19 Kong L，Li S，Han X，et al. Inhibition of HCV RNA-dependent RNA polymerase activity by aqueous extract from Fructus Ligustri Lucidi［J］.Virus Research，2007，128(1)：9～17.
20 Ma D, Shan A, Chen Z, et al. Effect of Ligustrum lucidum and Schisandra chinensis on the egg production, antioxidant status and immunity of laying hens during heat stress［J］. Archives of animal nutrition, 2005, 59(6): 439～447.
21 Ma D, Liu Y, Liu S, et al. Influence of Ligustrum lucidum and Schisandra chinensis fruits on antioxidative metabolism and immunological parameters of layer chicks［J］. Asian-Australasian Journal of Animal Sciences, 2007, 20(9): 1438～1443.
22 Ovesna Z, Kozics K, Slaminova D.Protective effects of ursolic acid and oleanolic acid in leukemic cells［J］. Mutate Research, 2006, 600(12)：131～137.
23 Shoemaker M, Hamilton B, Dairkee S H, et al.In vitro anticancer activity of twelve Chinese medicinal herbs［J］. Phytotheapyr Research, 2005, 19(7)：649～651.
24 Yin Y S, Yu C S. Study on chemical components and hepatoprotective properties of Ligustrum lucidum Ait［J］. Chin Tradit Patent Med, 1993, 15：18～19.

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Effects of Ligustrum lucidum Fruits Extracts on Productive Performance and Immune Function of Layer after Laying Peak Period

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