白细胞介素-16的研究进展

China Animal Husbandry & Veterinary Medicine ›› 2011, Vol. 38 ›› Issue (5): 163-166.

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Research Progress of Interleukin-16

WU Song-ming¹, ZHU Xing-quan^1,2, YUAN Zi-guo¹

1. College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China;2. State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046,China

Received:2010-11-21 Revised:1900-01-01 Online:2011-05-20 Published:2011-05-20

Abstract

Abstract: Interleukin-16 is a kind of pro-inflammatory cytokines and secretory proteins,secreted by CD8^＋T cell. Initially,it was described as lymphocyte chemoattractant factor,officially named as interleukin-16 in 1995. Since it’s cloned,its structure and function have been researched extensively, besides, there’s a certain study about its bioactivity. IL-16 is characterized as a chemoattractant for various immune cells,which plays a part in inflammation,allergy,autoimmune and other diseases. Recently,there is much research about the relationship between bioactivity and diseases. So according to current data,this review summarized IL-16 structure,biology function,the relationship between diseases and practical application.

Key words: interleukin-16; biology function; diseases; practical application

CLC Number:

Q516

WU Song-ming;ZHU Xing-quan;YUAN Zi-guo. Research Progress of Interleukin-16[J]. China Animal Husbandry & Veterinary Medicine, 2011, 38(5): 163-166.

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