外泌体对动物肠道健康的影响及其研究方法

doi:10.16431/j.cnki.1671-7236.2022.02.019

Abstract

Abstract: In the context of non-resistant breeding, the intestinal health of animals has attracted more and more attention.The intestinal tract is the main organ for digestion and absorption of nutrients, as well as the innate barrier to prevent intestinal microbial invasion.The integrity of the intestinal barrier function plays a crucial role in the normal growth and development of the body.Exosome is an endogenous regulatory substance that can be used as a starting point to solve intestinal health problems.Exosomes are nanoscale extracellular vesicles secreted by various types of cells, which are widely distributed in various body fluids and can carry bioactive substances such as proteins, nucleic acids and lipids.They participate in cell-to-cell transmission, cell migration and proliferation and play a role in physiological and pathological processes of the body.Recent studies have shown that exosomes can repair the intestinal barrier function of animals by regulating the composition of intestinal flora and inducing the proliferation of intestinal stem cells.In this paper, the effects of exosomes on intestinal health of livestock and poultry in recent years and the research methods of exosomes are reviewed and summarized to provide reference for subsequent studies.

Key words: intestinal; exosomes; biological function

CLC Number:

S813.1

WEI Wenzhuo, LIANG Zhenhua, WU Yan, LIU Jingbo, PI Jinsong, ZHANG Hao. Effects of Exosomes on Animal Intestinal Health and Its Research Methods[J]. China Animal Husbandry & Veterinary Medicine, 2022, 49(2): 579-586.

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Effects of Exosomes on Animal Intestinal Health and Its Research Methods

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