共轭亚油酸的生物学功能及其在动物生产中的应用

doi:10.16431/j.cnki.1671-7236.2019.11.010

Abstract

Abstract: As a natural new functional fatty acid,conjugated linoleic acid (CLA) has anti-hypertensive,anti-cancer,anti-diabetic and other biological properties,and its main active isomers play different roles.In recent years,with the decrease of CLA artificial synthesis cost and the deep researches in the field of animal nutrition,it was found that CLA can inhibit the expression and production of pro-inflammatory factors,promote the production of anti-inflammatory factors,and achieve anti-inflammatory effects,it can also regulate lymphocyte proliferation and differentiation,macrophage activity,promote antibody synthesis,regulate humoral immunity and cellular immunity,thereby enhancing animal immunity.CLA can also regulate the expression of a variety of nuclear transcription factors,affect fatty acid uptake and oxidation,as well as lipid anabolism,thereby reducing body fat deposition,increasing intramuscular fat content,changing fatty acid composition,and improving meat quality.Therefore,CLA has potential application value and broad market prospects in animal husbandry production.The article mainly introduced the roles of CLA in anti-inflammatory,immune function,lipid metabolism and anti-oxidation,and reviewed the biological functions of CLA and its application researches in animal production.In addition,CLA was also discussed as a feed additive,including its synthetic purity,optimal addition amount in different types of animals,different ages,feeding methods,in order to provide a theoretical reference for its rational application in animal production.

Key words: conjugated linoleic acid(CLA); anti-inflammatory; immune regulation; lipid metabolism; anti-oxidation

CLC Number:

S816.7

YANG Mei, MA Jie, YANG Tai, YAN Zhaoming, CHEN Qinghua. Biological Function of Conjugated Linoleic Acid and Its Application in Animal Production[J]. China Animal Husbandry & Veterinary Medicine, 2019, 46(11): 3216-3224.

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Biological Function of Conjugated Linoleic Acid and Its Application in Animal Production

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