Abstract:

This experiment was aimed to study the effects of Monascus synbiotic, yeast-selenium-germanium culture and their compound preparation instead of antibiotics on gut structure and rectal flora of weaned piglets.Eighty healthy piglets ((7.57±0.49) kg) were randomly divided into 4 groups with 5 replicates each group and 4 piglets each replicate.The control group was fed basal diet with 25 mg/kg colistin sulfate and 45 mg/kg chlortetracycline and groups Ⅰ, Ⅱ and Ⅲ were fed basic diet with 0.5% Monascus synbiotics, 0.5% Monascus synbiotics and yeast-selenium-germanium culture compound, 0.5% yeast-selenium-germanium culture, respectively.The test period was 42 d with 3 stages.The results showed that:①Compared with the control group, the activities of SOD and GSH-Px, T-AOC of the jejunum mucosa in the groups Ⅰ, Ⅱ and Ⅲ were extremely significantly or significantly increased (P<0.01;P<0.05).Compared with the group Ⅲ, the SOD activity and T-AOC of the jejunum mucosa in group Ⅱ were significantly increased (P<0.05).②Compared with the control group, the villus length and the V/C of the duodenum in the group Ⅰ, Ⅱ and Ⅲ were extremely significantly or significantly increased (P<0.01;P<0.05).And the V/C of jejunum in group Ⅱ was significantly increased (P<0.05).③At 1-14 d, compared with the control group, the number of Salmonella and E.coli in the groups Ⅰ and Ⅱ were significantly decreased (P<0.05).The number of Bifidobacteria and lactic acid bacteria showed a significant or extremely significant increase (P<0.05;P<0.01).At 15-28 d, compared with the control group, the number of lactic acid bacteria in groups Ⅰ, Ⅱ and Ⅲ was extremely significant or significantly increased (P<0.01;P<0.05).In conclusion, compared with antibiotics, Monascus synbiotics or yeast-selenium-germanium culture, their compound preparation could effectively improve the intestinal tissue structure and intestinal flora of weaned pigs.

Key words: Monascus synbiotic; selenium; germanium; piglets; intestinal structure