China Animal Husbandry & Veterinary Medicine ›› 2015, Vol. 42 ›› Issue (4): 1032-1037.doi: 10.16431/j.cnki.1671-7236.2015.04.40

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Effects Comparison of Fuzheng Jiedu San and its Super Micropowder on Anti-IBDV in Vitro

MA Xia1, GUO Zhen-huan2, LIU Yong-lu1, WANG Chang-lin1, ZHANG Guo-zu1,2   

  1. 1. Henan University of Animal Husbandry and Economy, Zhengzhou 450011, China;
    2. Henan Province Health Star Pharmaceutical Co., Ltd., Zhengzhou 451464, China
  • Received:2014-10-08 Online:2015-04-20 Published:2015-05-05

Abstract: In this study, we compared the effects of Fuzheng Jiedu super micropowder (FZSM) and Fuzheng Jiedu san (FZ) on anti-IBDV in vitro. Method of chicken embryo, 10-day-old SPF chicken embryos were inoculated with FZSM and FZ in three safe concentrations by two pathways of adding decoction before inoculation of virus and adding decoction after inoculation of virus, and then the effects of two decoctions on ELD50 of IBDV to 10-day-old SPF chicken embryos were measured. Method of cell, CEF was inoculated with FZSM and FZ in three safe concentrations by two pathways of adding decoction before inoculation of virus and adding decoction after inoculation of virus, and then the effects of two decoctions on CPE of IBDV to CEF were observed. The results showed that the virus titer and inhibition rate of CPE of IBDV were reduced by FZSM and FZ, the effect of high concentration was better than its low concentration, at the same concentration, the anti-IBDV effect of FZSM was superior to that of FZ, and preventive effect was better than therapeutic action. These results indicated that FZSM and FZ had the function of anti-IBDV in vitro and the effect of FZSM was superior to FZ.

Key words: Fuzheng Jiedu san; super micropowder; in vitro; antiviral effect

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