2株高致病性猪繁殖与呼吸综合征病毒分子特征分析

Abstract

Abstract: In order to find out the graph variation characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) of Qianxinanin Guizhou province, the Nsp2 and GP5 genes of PRRSV isolated strain GZLPS and GZSB were cloned, sequenced and analyzed. The results showed that, the Nsp2 gene of 2 isolates contained 90 nucleotides for discontinuous deletion and 36 nucleotides for mutation. Furthermore, there were different replacements of nucleotides in GP5 gene. Not only Nsp2 gene, but also GP5 gene, the nucleotide homologies were above 96% and the amino acid homologies were above 95% with strain JXA1 and isolates in Guzizhou since 2011, but there were differencex in molecular variation among these strains. It indicated that the PRRSV had already behaved diverse on variation style of Qianxinan in Guizhou province.

Key words: highly pathogenic porcine reproductive and respiratory syndrome virus; molecular characteristics; analysis; Nsp2; GP5

LUO Cheng-bo, CUI Min, KONG Ling-ping, CHENG Zhen-tao, ZHOU Bi-jun, MAO Li-hong. Molecular Characteristics Analysis of Two Strains of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus[J]. China Animal Husbandry & Veterinary Medicine.

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Molecular Characteristics Analysis of Two Strains of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

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