驼乳脂肪球膜蛋白功能特性及组成差异性的研究进展

doi:10.16431/j.cnki.1671-7236.2026.02.011

Abstract

Abstract:

Camel milk fat exists in the form of fat globules. The milk fat globule membrane （MFGM） is a three-layer membrane structure wrapped around the exterior of fat globules. This three-layer membrane with biologically active functions is mainly composed of proteins， enzymes， triacylglycerol and polar lipids （cholesterol， sphingolipids， etc.）. MFGM protein has received extensive attention due to its excellent biological activity functions and nutritional value. The author mainly reviewed the composition distribution and core functional characteristics of MFGM protein in camel milk， including its antibacterial， immunomodulatory， emulsifying stabilizing and tumor intervention effects. And from the perspective of proteomics， the differences in the composition and functional characteristics of the main MFGM proteins between camel milk and other milk sources such as cow milk and goat milk were briefly described. The influence of different processing techniques on the MFGM protein in camel milk was analyzed.An in-depth analysis of the functional properties and differential mechanisms of camel milk MFGM proteins will not only help elucidate the nutritional value of camel milk but also provide a theoretical foundation for the development of camel milk MFGM protein-based products.

Key words: camel milk; milk fat globule membrane; protein composition; function characteristics

CLC Number:

S872

ZHAO Yan, DUO Qianqian, XU Xiaowei, ZHENG Nan, CHEN He, ZHANG Shiqi, ZHAO Yankun. Research Progress on the Functional Characteristics and Compositional Differences of Fat Globule Membrane Proteins in Camel Milk[J]. China Animal Husbandry & Veterinary Medicine, 2026, 53(2): 631-638.

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References 67

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蛋白质 Proteins	分子质量 Molecular mass/ku	功能特性 Functional characteristics	参考文献 References
MUC1	160~200	抑菌	Lindén等^［18］
XO/XDH	150	参与氧化还原反应，消炎、抗菌	Harrison^［19］、Martin等^［20］
BTN	67	调节乳脂肪球的产生和分泌；参与调节婴儿免疫系统	温欣怡等^［21］
FABP	13~15	抗癌；参与脂质运输和脂质代谢的调节	Spistberg等^［22］
MFG-E8	47~59	维持上皮稳态以及促进黏膜愈合和磷脂结合；抗癌	Kulyar等^［23］

Research Progress on the Functional Characteristics and Compositional Differences of Fat Globule Membrane Proteins in Camel Milk

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