马胎盘滋养层细胞研究进展

doi:10.16431/j.cnki.1671-7236.2025.11.005

Abstract

Abstract: During the gestation period of equine animals,trophoblast cells play a crucial role in various physiological processes such as embryo implantation,vascular remodeling at the maternal-fetal interface,and the exchange of nutrients and gases between the mother and the fetus.Due to the long period of migration of equine embryos within the uterus,the author briefly described the biological significance of equine embryo trophoblast cells in embryo positioning,pregnancy recognition,and maintaining pregnancy.Through elaborating on the regulatory mechanisms of steroid hormones,growth factors,and immune cytokines on trophoblast cells,the aim is to reveal their effects on the biological activity of trophoblast cells.At present,the research on equine trophoblast cells is still not complete.In the future,it may be possible to utilize new technologies such as single-cell sequencing and organoid culture to reveal the developmental regulatory patterns of these cells.Meanwhile,through multi-omics analysis,biomarkers suitable for early pregnancy diagnosis were identified to enhance the survival rate and reproductive efficiency of equine embryos.Furthermore,based on the reproductive characteristics of equine animals,the application of targeted nutritional regulation strategies and immune intervention methods can provide new ideas for improving the reproductive performance of horses.

Key words: horse; trophoblast cells; early pregnancy; placenta formation; regulatory mechanisms

CLC Number:

S821.3

HAO Asiya, MU Siqin, YI Minna, WEN Xin, BOU Gerelchimeg. Research Progress on Trophoblast Cells of Horse Placenta[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(11): 5063-5073.

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Research Progress on Trophoblast Cells of Horse Placenta

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