China Animal Husbandry & Veterinary Medicine ›› 2025, Vol. 52 ›› Issue (8): 3651-3660.doi: 10.16431/j.cnki.1671-7236.2025.08.014

• Nutrition and Feed • Previous Articles    

Effects of Sodium Butyrate and Ampelopsis grossedentata Flavonoids on Production Performance, Diarrhea and Serum Indicators in Australian-Canadian F1 Holstein Weaned Calves

ZHANG Lijuan1, ZHAO Minlin1, ZHANG Meng1, ZHANG Hao1, HUANG Qin1, JIANG Feng1, YIN Fuyao1, ZHANG Lixin1, DU Zhiyong1, YANG Runcheng2, WAMG Lixing3, LI Qing1   

  1. 1. Faculty of Animal Science and Technology, Yunnan Agricultural University, Key Laboratory of Animal Nutrition and Feed, Yunnan Province, Kunming 650201, China;
    2. Heqing Holstein Farming Limited Company, Heqing 671504, China;
    3. Yunnan Animal Husbandry Station, Kunming 650224, China
  • Received:2024-10-16 Published:2025-08-02

Abstract: 【Objective】 This experiment aimed to study the effect of sodium butyrate and Ampelopsis grossedentata flavonoids in the basal diet of Holstein weaned calves on their production performance,diarrhea and serum indicators. 【Method】 28 Australian-Canadian F1 Holstein female calves of similar age and body weight were randomly divided into 4 groups with 7 heads each.The calves in control group (group Ⅰ) were fed the basal diet,in experimental groups were supplemented with 3 g/kg DM sodium butyrate (group Ⅱ),8 g/kg DM Ampelopsis grossedentata flavonoids (group Ⅲ) and 3 g/kg DM sodium butyrate + 8 g/kg DM Ampelopsis grossedentata flavonoids (group Ⅳ),respectively.The pretest period was 10 d and the pilot period was 60 d.After the experiment,the body weight and body size of weaned calves were measured,and body size index,the average daily gain (ADG),daily dry material food intake (DMI) and feed to gain ratio (F/G) of calves in each group were calculated.The fecal stool of each calf was collected and the fecal moisture rate was measured.The fecal situation of each calf in each group was observed and recorded every day,and the diarrhea rate of calves was measured and fecal score was performed.Blood samples from tail root vein were collected to determine the serum biochemical indicators. 【Result】 ①The final body weight and ADG of calves in group Ⅲ were significantly higher than those in groupⅠ (P<0.05),and DMI was significantly higher than groups Ⅰ,Ⅱ and Ⅳ (P<0.05).②The withers height of calves in group Ⅲ was significantly higher than that of groups Ⅰ and Ⅳ (P<0.05),the pipe circumference of calves in groups Ⅲ and Ⅳ were significantly higher than that of group Ⅰ,and pipe circumference index of calves in group Ⅳ was significantly higher than that of group Ⅰ (P<0.05);③At 60 days,the fecal moisture rate of calves in groups Ⅱ and Ⅲ were significantly lower than that in group I (P<0.05),and the average fecal scores and diarrhea rate of calves in group Ⅲ were significantly lower than that of group Ⅰ (P<0.05).④The content of cholesterol (CHOL) in serum of calves in groups Ⅱ and Ⅲ were significantly higher than that in groups Ⅰ and Ⅳ (P<0.05),the content of insulin-like growth factor-1 (IGF-1) in serum of calves in groups Ⅱ and Ⅲ were significantly higher than that in group Ⅰ (P<0.05). 【Conclusion】 The addition of 8 g/kg DM Ampelopsis grossedentata flavonoids in the basal diet could reduce the diarrhea and improve the growth performance of Australian-Canadian F1 Holstein weanded calves.

Key words: Holstein weaned calves; diarrhoea rate; growth performance; serum indicators

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