猪群疫病mRNA疫苗研究进展

doi:10.16431/j.cnki.1671-7236.2025.09.031

Abstract

Abstract: mRNA vaccine,which encodes the target protein or polypeptide antigens,can be delivered to cells for translation to induce an immune response against pathogens.Given the urgent need to prevent and control swine diseases,traditional vaccines can’t fully meet the needs of epidemic prevention.With short development time,high safety and strong immune efficacy,mRNA vaccines have become one of the main research directions for the prevention and control of animal diseases.Effective mRNA vaccines can reduce the incidence and spread of swine diseases.The authors summarised the types and structures of mRNA vaccines,key technologies and research progress of mRNA vaccines for porcine epidemic diarrhea,foot-and-mouth disease,porcine reproductive and respiratory syndrome,African swine fever,porcine pseudorabies,swine influenza and other swine diseases.The application of mRNA vaccines in the prevention and control of swine diseases was further prospected to provide a reference for the development and production of mRNA vaccines for swine diseases.

Key words: mRNA vaccine; immunization; prevention; swine diseases

CLC Number:

S859.79^＋7

YIN Jingqi, SHA Zhou, ZHANG Haiguang, CUI Jin, ZHENG Hui, DONG Yaqin, WEI Rong, GU Shaopeng, NI Bo. Research Progress of mRNA Vaccine for Swine Diseases[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(9): 4346-4357.

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Research Progress of mRNA Vaccine for Swine Diseases

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