Abstract: 40 egg-laying chickens of 14-day-old were randomly divided into two groups, control and treatment. There were 20 chicks in each group. Newcastle vaccines (0.2ml/chick) were injected to cervical subcutaneous of control, and treatment was not only injected Newcastle vaccines, but also fed sustainedrelease compound immunopotentiator (1 particle/chick). Treatment were noticeably higher(P＜0.01) than control in Newcastle disease (ND) HI antibody valence, rate of ERFC and positive ratio of ANAE after detected in 10, 20, 30 and 40 d; in addition, the growth of relative weight of the immune organs on treatment could be obviously promoted, compared with control, and ratio of chicken bursa and spleen also did, but the difference of them was not obvious(P＞0.05).Therefore, the sustainedrelease compound immunopotentiator developed was an effective and less sideeffect immunopotentiator that had significant effect of immunoenhancement , disappeared slowly in delay phase ,and as well could promote the growth of organism.

Key words: chicken; sustainedrelease compound immunopotentiator; immune function; immunoenhancement effect