黄曲霉毒素B1的毒性机理、检测及脱毒方法研究进展

doi:10.16431/j.cnki.1671-7236.2025.08.043

Abstract

Abstract: Aflatoxins are mainly toxic secondary metabolites produced by fungi such as Aflatus and Aspergillus parasiticus under suitable environmental conditions.They are widely present in food and feed,posing a great threat to human and animal health,and have become a major problem in the field of food and feed safety.Aflatoxin B₁(AFB₁) is one of the most harmful mycotoxins,which has high toxicity and strong carcinogenicity for humans and animals.Its toxicity mainly includes liver toxicity,neurotoxicity,intestinal toxicity,immunotoxicity and reproductive toxicity.How to effectively detect and detoxification aflatoxin B₁ has been a research hotspot at home and abroad.Traditional detection methods such as chromatography or immunoassay have been widely used for a long time,and with the progress of science and technology,some new detection methods have been developed with higher accuracy and sensitivity.In terms of detoxification,compared with physical and chemical detoxification,biological detoxification has become a current research hotspot due to its unique advantages and has better application potential.In this paper,the toxicity mechanism,detection methods and detoxification methods of aflatoxin B₁ will be comprehensively reviewed based on the latest scientific research results,the advantages and limitations of different detection and detoxification methods will be discussed,the feasibility of their practical application will be evaluated,and the future development direction will be looked forward to in order to provide a more solid theoretical basis for the research of aflatoxin B₁.Therefore,it can effectively reduce the threat of aflatoxins to human and animal health,and ensure food safety and public health.

Key words: aflatoxin B₁; physical and chemical properties; toxicity mechanism; detection methods; detoxification methods

CLC Number:

S852.4^＋4

JIA Kejiang, WU Guofang, ZHANG Jianbo, LUO Xuan, WANG Lei. Research Progress on Toxicity Mechanism,Detection and Detoxification Methods of Aflatoxin B₁[J]. China Animal Husbandry & Veterinary Medicine, 2025, 52(8): 3954-3964.

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Research Progress on Toxicity Mechanism,Detection and Detoxification Methods of Aflatoxin B₁

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Research Progress on Toxicity Mechanism,Detection and Detoxification Methods of Aflatoxin B1

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Research Progress on Toxicity Mechanism,Detection and Detoxification Methods of Aflatoxin B₁