无乳链球菌致病性研究进展

doi:10.16431/j.cnki.1671-7236.2024.03.040

Abstract

Abstract: Streptococcus agalactiae (S. agalactiae) is a widely distributed zoonotic pathogen.It can survive indefinitely in mammary glands of cows,by forming a biofilm that allows them to adhere and persist in the mammary gland,concomitantly enhancing resistance to host immune defense.S. agalactiae causes sub-clinical mastitis,which is one of the most common pathogens leading to mastitis in dairy herds worldwide,which causes huge economic losses to dairy industry.In addition,S. agalactiae can also infect various animals such as Camelus and Oreochromis niloticus,causing serious deterioration in animal welfare,and there is a possibility of indirect transmission between humans and animals. S. agalactiae is a Gram positive opportunistic pathogen that can asymptotically colonize the gastrointestinal and urogenital tracts of healthy adults.Infection of newborns can lead to life-threatening sepsis and meningitis,often accompanied by severe neurological sequelae.In recent years,the incidence rate of adult S. agalactiae infection is on the rise,especially for pregnant women,the elderly and people with low immunity.It can cause skin and soft tissue infections and more serious septicemia,meningitis,endocarditis and other diseases.Although the symptoms can be partially alleviated by treatment with antibiotics,the emergence and spread of drug-resistant strains have gradually reduced the effectiveness of treatment,and the control of S. agalactiae infection becomes more and more difficult.In this paper,the author summarized the pathogenicity of S. agalactiae to humans and different animals,in order to provide reference for the prevention and control of S. agalactiae.

Key words: Streptococcus agalactiae; infection; pathogenicity

CLC Number:

S852.61

CHEN Jing, MA Jun, FAN Zhaowei, LIU Huiting, CUI Yudong. Research Progress on Pathogenicity of Streptococcus agalactiae[J]. China Animal Husbandry & Veterinary Medicine, 2024, 51(3): 1277-1285.

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Research Progress on Pathogenicity of Streptococcus agalactiae

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