表观遗传修饰在骨骼肌细胞增殖分化过程中的研究进展

doi:10.16431/j.cnki.1671-7236.2020.10.031

Abstract

Abstract: Skeletal muscle is the most abundant tissue and the main component of muscle in animals.The process of skeletal muscle cell's proliferation and differentiation is the basis of muscle development and it's directly affects the meat production performance of domestic animals.It has been found that epigenetic modification plays an important role in regulating the proliferation and differentiation of skeletal muscle cells.In this study,the effects of epigenetics on skeletal muscle in terms of the effects of DNA methylation on the proliferation and differentiation of skeletal muscle cells,the selection and expression of factors regulated by histone acetylation,the regulation of non-coding RNA,and the effects of chromosome remodeling.Research progress in the process of muscle cell proliferation and differentiation,briefly describes the effects of different modification methods and factors on the two processes of skeletal muscle proliferation and differentiation.At the same time,the methods and means used by predecessor in the study of skeletal muscle proliferation and differentiation were reviewed,and then the role of apparent regulatory factors in skeletal muscle growth was analyzed.The purpose was to further explain the important role of epigenetic modification in the proliferation and differentiation of skeletal muscle,enhanced the understanding of the regulation of skeletal muscle proliferation and differentiation,provided a reference path for integration with animal production,and also provided skeletal muscle.Molecular regulation of such as growth and development provided more reference materials.

Key words: epigenetic modification; skeletal muscle; proliferation; differentiation

CLC Number:

S813.1

JING Jing, YAO Dong, LING Yinghui. Research Progress of Epigenetics Modification in the Process of Skeletal Muscle Cell Proliferation and Differentiation[J]. China Animal Husbandry & Veterinary Medicine, 2020, 47(10): 3314-3322.

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Research Progress of Epigenetics Modification in the Process of Skeletal Muscle Cell Proliferation and Differentiation

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