Abstract: This experiment was conducted to assess the rehabilitation of immune organ of affected chicken for infectious bursal disease (IBD) was repaired by herbal-medicine pellets. The recovered chickens infected by IBD of control group not using drug and treatment group using the granular formulation of herbal-medicine pellets were killed, and their immune organs were performed to evaluate the histopathology change under the microscope. Ten twenty-five-day chickens were selected at random from control group not using drug and treatment group using the granular formulation of herbal-medicine pellets respectively. After ten days, all selected chickens from treatment group were recovered, whereas three of ten chickens from treatment group were died. Bursa of Fabricius, spleen and liver of each chicken were collected, observed. The tissues of these organs were fixed using 10% Formalin solution, embedded by paraffin. Embedded tissues were sliced up, stained and then observed. The histopathology photographs were conducted to assess the pathology change of immune organ from recovered chickens infected by IBD of control group not using drug and treatment group using the granular formulation of herbal-medicine pellets. Histopathology change was low grade in control group, where as no histopathology change was observed in treatment group. Immunoenhancement was showed in treatment group. Impairment of immune organ of affected chicken for IBD can be repaired markedly using the granular formulation of herbal-medicine pellets.

Key words: herbal-medicine pellets; immune organ; pathology